21 C.F.R. § 522.1452 Nalorphine hydrochloride injection.
Title 21 - Food and Drugs
(a) Specifications. Each milliliter of aqueous solution contains 5 milligrams of nalorphine hydrochloride. (b) Sponsor. See No. 050604 in §510.600(c) of this chapter. (c) Conditions of use—(1) Amount. One milligram per 5 pounds; intravenously, intramuscularly, or subcutaneously. (2) Indications for use. Respiratory and circulatory depression in dogs resulting from overdosage of, or unusual sensitivity to, morphine and certain other narcotics. Not for depression due to any other cause. (3) Limitations. Successive doses of the drug gradually lose their analeptic effect and eventually induce respiratory depression equal to that of opiates. Therefore, do not exceed therapeutic dosage. Do not mix drug with meperidine solutions because the buffer will cause precipitation. Federal law restricts this drug to use by or on the order of a licensed veterinarian. [44 FR 6707, Feb. 2, 1979, as amended at 47 FR 36418, Aug. 20, 1982; 62 FR 63271, Nov. 28, 1997]
Title 21: Food and Drugs
PART 522—IMPLANTATION OR INJECTABLE DOSAGE FORM NEW ANIMAL DRUGS
§ 522.1452 Nalorphine hydrochloride injection.
