21 C.F.R. § 558.530 Roxarsone.
Title 21 - Food and Drugs
(a) Specifications. Type A medicated articles containing 10, 20, 50, or 80 percent roxarsone. (b) Approvals. See sponsors in §510.600(c) of this chapter for use as in paragraph (d) of this section. (1) No. 046573 for use of 10, 20, and 50 percent Type A medicated articles as in paragraph (d)(1)(i) of this section. (2) No. 046573 for use of 10, 20, 50, and 80 percent Type A medicated articles as in paragraphs (d)(1) through (d)(3) of this section. (c) Related tolerances. See §556.60 of this chapter. (d) Conditions of use—(1) Chickens. It is used in chicken feed as follows: (2) Turkeys. It is used in turkey feed as follows: (3) Swine. It is used in swine feed as follows: (4) Permitted combinations. It may be used in accordance with this section in combination with: (i) Aklomide as in §558.35. (ii) Amprolium as in §558.55. (iii) Amprolium and ethopabate as in §558.58. (iv) Bacitracin methylene disalicylate as in §558.76. (v) Bacitracin zinc as in §558.78. (vi) Bambermycins and bambermycins plus certain anticoccidials as in §558.95. (vii) Chlortetracycline as in §558.128. (viii) Clopidol as in §558.175. (ix) Decoquinate alone or in combination as in §558.195. (x) Diclazuril alone or in combination as in §558.198. (xi) Halofuginone alone or in combination as in §558.265. (xii) Lasalocid alone or in combination as in §558.311. (xiii) Monensin alone or in combination as in §558.355. (xiv) Narasin alone or in combination as in §558.363. (xv) Nequinate as in §558.365. (xvi) Nicarbazin alone or in combination as in §558.366. (xvii) Nitromide and sulfanitran as in §558.376. (xviii) Penicillin and zoalene as in §558.680. (xix) Robenidine hydrochloride as in §558.515. (xx) Salinomycin alone or in combination as in §558.550. (xxi) Semduramicin alone or in combination as in §558.555. (xxii) Sulfadimethoxine, ormetoprim as in §558.575. (xxiii) Zoalene alone or in combination as in §558.680. [46 FR 52331, Oct. 27, 1981] Editorial Note: For
Title 21: Food and Drugs
PART 558—NEW ANIMAL DRUGS FOR USE IN ANIMAL FEEDS
Subpart B—Specific New Animal Drugs for Use in Animal Feeds
§ 558.530 Roxarsone.
------------------------------------------------------------------------Roxarsone in Combinations grams per in grams per Indications Limitations Sponsor ton ton for use------------------------------------------------------------------------(i) 22.7 to .............. Growing Feed 046573 45.4 chickens: continuously For throughout increased growing rate of period; do weight gain, not feed to improved chickens feed producing efficiency, eggs for and improved human pigmentation consumption; . withdraw 5 days before slaughter; as sole source of organic arsenic; drug overdose or lack of water may result in leg weakness.------------------------------------------------------------------------(ii) 22.7 to Chlortetracycl Growing As in ........... 45.4 ine 10 to 50 chickens: As paragraph in paragraph (d)(1)(i) of (d)(1)(i) of this section. this Chlortetracyc section. line as provided by No. 046573 in § 510.600(c) of this chapter.------------------------------------------------------------------------(iii) 22.7 Chlortetracycl Growing As in ........... to 45.4 ine 100 to chickens: As paragraph 200 in paragraph (d)(1)(i) of (d)(1)(i) of this section this except feed section; and continuously for control for 7 to 14 of days. infectious Chlortetracyc synovitis line as caused by provided by Mycoplasma No. 046573 in synoviae § susceptible 510.600(c) of to this chapter. chlortetracy cline.------------------------------------------------------------------------(iv) 22.7 to Chlortetracycl Growing As in ........... 45.4 ine 200 to chickens: As paragraph 400 in paragraph (d)(1)(i) of (d)(1)(i) of this section this except feed section; and continuously for control for 7 to 14 of chronic days. respiratory Chlortetracyc disease line as (CRD) and provided by air sac No. 046573 in infection § caused by M. 510.600(c) of gallisepticu this chapter. m and Escherichia coli susceptible to chlortetracy cline.------------------------------------------------------------------------(v) 22.7 to Chlortetracycl Growing As in ........... 45.4 ine 500 chickens: As paragraph in paragraph (d)(1)(i) of (d)(1)(i) of this section this except feed section; and continuously for for 5 days. reduction of Chlortetracyc mortality line as due to E. provided by coli No. 046573 in infections § susceptible 510.600(c) of to this chapter. chlortetracy cline.------------------------------------------------------------------------
------------------------------------------------------------------------Roxarsone in Combinations grams per in grams per Indications Limitations Sponsor ton ton for use------------------------------------------------------------------------(i) 22.7 to .............. Growing Feed 046573 45.4 turkeys: For continuously increased throughout rate of growing weight gain, period; do improved not feed to feed turkeys efficiency, producing and improved eggs for pigmentation human . consumption; withdraw 5 days before slaughter; as sole source of organic arsenic; drug overdose or lack of water may result in leg weakness.------------------------------------------------------------------------(ii) 22.7 to Chlortetracycl Growing As in ........... 45.4 ine 10 to 50 turkeys: As paragraph in paragraph (d)(2)(i) of (d)(2)(i) of this section. this Chlortetracyc section. line as provided by No. 046573 in § 510.600(c) of this chapter.------------------------------------------------------------------------(iii) 22.7 Chlortetracycl Growing As in ........... to 45.4 ine 200 turkeys: As paragraph in paragraph (d)(2)(i) of (d)(2)(i) of this section this except feed section; and continuously for control for 7 to 14 of days. infectious Chlortetracyc synovitis line as caused by provided by Mycoplasma No. 046573 in synoviae § susceptible 510.600(c) of to this chapter. chlortetracy cline.------------------------------------------------------------------------(iv) 22.7 to Chlortetracycl 1. Growing As in ........... 45.4 ine 400 turkeys: As paragraph in paragraph (d)(2)(i) of (d)(2)(i) of this section this except feed section; and continuously for control for 7 to 14 of days. hexamitiasis Chlortetracyc caused by line as Hexamita provided by meleagrides No. 046573 in susceptible § to 510.600(c) of chlortetracy this chapter. cline. 2. Turkey poults not over 4 weeks of age: Reduction of mortality due to paratyphoid caused by Salmonella typhimurium susceptible to chlortetracy cline.------------------------------------------------------------------------(v) 22.7 to Chlortetracycl Growing As in ........... 45.4 ine 25 mg/lb turkeys: As paragraph body weight in paragraph (d)(2)(i) of daily (d)(2)(i) of this section this except feed section; and continuously for control for 7 to 14 of days. complicating Chlortetracyc bacterial line as organisms provided by associated No. 046573 in with § bluecomb 510.600(c) of (transmissib this chapter. le enteritis, coronaviral enteritis) susceptible to chlortetracy cline.------------------------------------------------------------------------
------------------------------------------------------------------------Roxarsone in Combinations grams per in grams per Indications Limitations Sponsor ton ton for use------------------------------------------------------------------------(i) 22.7 to .............. Growing and Feed 046573 34.1 finishing continuously swine: For throughout increased growing rate of period; weight gain withdraw 5 and improved days before feed slaughter; as efficiency. sole source of organic arsenic.------------------------------------------------------------------------(ii) 22.7 to Chlortetracycl Growing and Feed for not ........... 34.1 ine 400 (to finishing more than 14 administer 10 swine: As in days; mg/lb body paragraph withdraw 5 weight) (d)(3)(i) of days before this slaughter; as section; and sole source for of organic treatment of arsenic. bacterial enteritis caused by E. coli and S. choleraesuis and bacterial pneumonia caused by Pasteurella multocida susceptible to chlortetracy cline.------------------------------------------------------------------------(iii) 181.5 .............. Growing and Feed for not 046573 finishing more than 6 swine: For consecutive the days; if treatment of improvement swine is not dysentery. observed, consult a veterinarian; withdraw 5 days before slaughter; as a sole source of organic arsenic; animals must consume enough medicated feed to provide a therapeutic dose.------------------------------------------------------------------------(iv) 181.5 Chlortetracycl Growing and Feed for not ........... ine 10 to 50 finishing more than 6 swine: As in consecutive paragraph days; if (d)(3)(i) of improvement this is not section; and observed, for consult a treatment of veterinarian; swine withdraw 5 dysentery. days before slaughter; as a sole source of organic arsenic; animals must consume enough medicated feed to provide a therapeutic dose.------------------------------------------------------------------------(v) 181.5 Chlortetracycl Growing and Feed for not ........... ine 400 (to finishing more than 6 administer 10 swine: As in consecutive mg/lb body paragraph days; if weight) (d)(3)(iii) improvement of this is not section; and observed, for consult a treatment of veterinarian; bacterial withdraw 5 enteritis days before caused by E. slaughter; as coli and S. a sole source choleraesuis of organic and arsenic; bacterial animals must pneumonia consume caused by P. enough multocida medicated susceptible feed to to provide a chlortetracy therapeutic cline. dose.------------------------------------------------------------------------
