21 C.F.R. § 558.600 Tiamulin.
Title 21 - Food and Drugs
(a) Specifications. Type A article containing 5, 10, or 113.4 grams of tiamulin (as tiamulin hydrogen fumarate) per pound. (b) Approvals. See No. 058198 in §510.600(c) of this chapter. (c) Related tolerances. See §556.738 of this chapter. (d) Special considerations—(1) Swine being treated with tiamulin should not have access to feeds containing polyether ionophores (e.g., lasalocid, monensin, narasin, salinomycin, or semduramycin) as adverse reactions may occur. If signs of toxicity occur, discontinue use. (2) Not for use in swine weighing over 250 pounds. (3) Use as sole source of tiamulin. (e) Conditions of use—(1) Swine. It is used as follows: (2) [Reserved] [67 FR 7268, Feb. 19, 2002, as amended at 69 FR 62407, Oct. 26, 2004; 70 FR 75018, Dec. 19, 2005]
Title 21: Food and Drugs
PART 558—NEW ANIMAL DRUGS FOR USE IN ANIMAL FEEDS
Subpart B—Specific New Animal Drugs for Use in Animal Feeds
§ 558.600 Tiamulin.
---------------------------------------------------------------------------------------------------------------- Combination in grams Tiamulin in grams per ton per ton Indications for use Limitations Sponsor----------------------------------------------------------------------------------------------------------------(i) 10........................... .................... For increased rate of Feed continuously 058198 weight gain and as the sole ration. improved feed efficiency.(ii) 35.......................... .................... 1. For control of swine Feed continuously 058198 dysentery associated as sole ration on with Brachyspira premises with a (formerly Serpulina or history of swine Treponema) dysentery but hyodysenteriae where signs of susceptible to disease have not tiamulin. yet occurred or following approved treatment of disease. Withdraw 2 days before slaughter. .................... 2. For control of Feed continuously 058198 porcine proliferative as the sole ration enteropathies for not less than (ileitis) associated 10 days. Withdraw with Lawsonia 2 days before intracellularis. slaughter.(iii) 35......................... Chlortetracycline, For treatment of swine Feed continuously 048164, approximately 400 bacterial enteritis as sole ration for 058198 (varying with body caused by Escherichia 14 days. Use as weight and feed coli and Salmonella only source of consumption to choleraesuis and chlortetracycline. provide 10 bacterial pneumonia Withdraw 2 days milligrams of caused by Pasteurella before slaughter. chlortetracycline multocida susceptible As per pound of body to chlortetracycline, chlortetracycline weight daily). and control of swine calcium complex, dysentery associated Type A medicated with Brachyspira articles (formerly Serpulina or containing the Treponema) equivalent of 50 hyodysenteriae to 100 grams per susceptible to pound of tiamulin. chlortetracycline hydrochloride provided by 046573 and 048164 in § 510.600(c) of this chapter.(iv) 200......................... .................... For treatment of swine Feed continuously 058198 dysentery associated as the sole feed with Brachyspira for 14 consecutive (formerly Serpulina or days. Withdraw Treponema) feed 7 days before hyodysenteriae slaughter. susceptible to tiamulin.----------------------------------------------------------------------------------------------------------------
