21 C.F.R. PART 582—SUBSTANCES GENERALLY RECOGNIZED AS SAFE


Title 21 - Food and Drugs


Title 21: Food and Drugs

Browse Previous |  Browse Next

PART 582—SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Section Contents

Subpart A—General Provisions

§ 582.1   Substances that are generally recognized as safe.
§ 582.10   Spices and other natural seasonings and flavorings.
§ 582.20   Essential oils, oleoresins (solvent-free), and natural extractives (including distillates).
§ 582.30   Natural substances used in conjunction with spices and other natural seasonings and flavorings.
§ 582.40   Natural extractives (solvent-free) used in conjunction with spices, seasonings, and flavorings.
§ 582.50   Certain other spices, seasonings, essential oils, oleoresins, and natural extracts.
§ 582.60   Synthetic flavoring substances and adjuvants.
§ 582.80   Trace minerals added to animal feeds.
§ 582.99   Adjuvants for pesticide chemicals.

Subpart B—General Purpose Food Additives

§ 582.1005   Acetic acid.
§ 582.1009   Adipic acid.
§ 582.1033   Citric acid.
§ 582.1057   Hydrochloric acid.
§ 582.1061   Lactic acid.
§ 582.1069   Malic acid.
§ 582.1073   Phosphoric acid.
§ 582.1077   Potassium acid tartrate.
§ 582.1087   Sodium acid pyrophosphate.
§ 582.1091   Succinic acid.
§ 582.1095   Sulfuric acid.
§ 582.1099   Tartaric acid.
§ 582.1125   Aluminum sulfate.
§ 582.1127   Aluminum ammonium sulfate.
§ 582.1129   Aluminum potassium sulfate.
§ 582.1131   Aluminum sodium sulfate.
§ 582.1135   Ammonium bicarbonate.
§ 582.1137   Ammonium carbonate.
§ 582.1139   Ammonium hydroxide.
§ 582.1141   Ammonium phosphate.
§ 582.1143   Ammonium sulfate.
§ 582.1155   Bentonite.
§ 582.1165   Butane.
§ 582.1191   Calcium carbonate.
§ 582.1193   Calcium chloride.
§ 582.1195   Calcium citrate.
§ 582.1199   Calcium gluconate.
§ 582.1205   Calcium hydroxide.
§ 582.1207   Calcium lactate.
§ 582.1210   Calcium oxide.
§ 582.1217   Calcium phosphate.
§ 582.1235   Caramel.
§ 582.1240   Carbon dioxide.
§ 582.1275   Dextrans.
§ 582.1320   Glycerin.
§ 582.1324   Glyceryl monostearate.
§ 582.1355   Helium.
§ 582.1366   Hydrogen peroxide.
§ 582.1400   Lecithin.
§ 582.1425   Magnesium carbonate.
§ 582.1428   Magnesium hydroxide.
§ 582.1431   Magnesium oxide.
§ 582.1480   Methylcellulose.
§ 582.1500   Monoammonium glutamate.
§ 582.1516   Monopotassium glutamate.
§ 582.1540   Nitrogen.
§ 582.1585   Papain.
§ 582.1613   Potassium bicarbonate.
§ 582.1619   Potassium carbonate.
§ 582.1625   Potassium citrate.
§ 582.1631   Potassium hydroxide.
§ 582.1643   Potassium sulfate.
§ 582.1655   Propane.
§ 582.1666   Propylene glycol.
§ 582.1685   Rennet.
§ 582.1711   Silica aerogel.
§ 582.1721   Sodium acetate.
§ 582.1736   Sodium bicarbonate.
§ 582.1742   Sodium carbonate.
§ 582.1745   Sodium carboxymethylcellulose.
§ 582.1748   Sodium caseinate.
§ 582.1751   Sodium citrate.
§ 582.1763   Sodium hydroxide.
§ 582.1775   Sodium pectinate.
§ 582.1778   Sodium phosphate.
§ 582.1781   Sodium aluminum phosphate.
§ 582.1792   Sodium sesquicarbonate.
§ 582.1804   Sodium potassium tartrate.
§ 582.1810   Sodium tripolyphosphate.
§ 582.1901   Triacetin.
§ 582.1973   Beeswax.
§ 582.1975   Bleached beeswax.
§ 582.1978   Carnauba wax.

Subpart C—Anticaking Agents

§ 582.2122   Aluminum calcium silicate.
§ 582.2227   Calcium silicate.
§ 582.2437   Magnesium silicate.
§ 582.2727   Sodium aluminosilicate.
§ 582.2729   Hydrated sodium calcium aluminosilicate.
§ 582.2906   Tricalcium silicate.

Subpart D—Chemical Preservatives

§ 582.3013   Ascorbic acid.
§ 582.3021   Benzoic acid.
§ 582.3041   Erythorbic acid.
§ 582.3081   Propionic acid.
§ 582.3089   Sorbic acid.
§ 582.3109   Thiodipropionic acid.
§ 582.3149   Ascorbyl palmitate.
§ 582.3169   Butylated hydroxyanisole.
§ 582.3173   Butylated hydroxytoluene.
§ 582.3189   Calcium ascorbate.
§ 582.3221   Calcium propionate.
§ 582.3225   Calcium sorbate.
§ 582.3280   Dilauryl thiodipropionate.
§ 582.3336   Gum guaiac.
§ 582.3490   Methylparaben.
§ 582.3616   Potassium bisulfite.
§ 582.3637   Potassium metabisulfite.
§ 582.3640   Potassium sorbate.
§ 582.3660   Propyl gallate.
§ 582.3670   Propylparaben.
§ 582.3731   Sodium ascorbate.
§ 582.3733   Sodium benzoate.
§ 582.3739   Sodium bisulfite.
§ 582.3766   Sodium metabisulfite.
§ 582.3784   Sodium propionate.
§ 582.3795   Sodium sorbate.
§ 582.3798   Sodium sulfite.
§ 582.3845   Stannous chloride.
§ 582.3862   Sulfur dioxide.
§ 582.3890   Tocopherols.

Subpart E—Emulsifying Agents

§ 582.4101   Diacetyl tartaric acid esters of mono- and diglycerides of edible fats or oils, or edible fat-forming fatty acids.
§ 582.4505   Mono- and diglycerides of edible fats or oils, or edible fat-forming acids.
§ 582.4521   Monosodium phosphate derivatives of mono- and diglycerides of edible fats or oils, or edible fat-forming fatty acids.
§ 582.4666   Propylene glycol.

Subpart F—Nutrients and/or Dietary Supplements1

§ 582.5013   Ascorbic acid.
§ 582.5017   Aspartic acid.
§ 582.5049   Aminoacetic acid.
§ 582.5065   Linoleic acid.
§ 582.5118   Alanine.
§ 582.5145   Arginine.
§ 582.5159   Biotin.
§ 582.5191   Calcium carbonate.
§ 582.5195   Calcium citrate.
§ 582.5201   Calcium glycerophosphate.
§ 582.5210   Calcium oxide.
§ 582.5212   Calcium pantothenate.
§ 582.5217   Calcium phosphate.
§ 582.5223   Calcium pyrophosphate.
§ 582.5230   Calcium sulfate.
§ 582.5245   Carotene.
§ 582.5250   Choline bitartrate.
§ 582.5252   Choline chloride.
§ 582.5260   Copper gluconate.
§ 582.5271   Cysteine.
§ 582.5273   Cystine.
§ 582.5301   Ferric phosphate.
§ 582.5304   Ferric pyrophosphate.
§ 582.5306   Ferric sodium pyrophosphate.
§ 582.5308   Ferrous gluconate.
§ 582.5311   Ferrous lactate.
§ 582.5315   Ferrous sulfate.
§ 582.5361   Histidine.
§ 582.5370   Inositol.
§ 582.5375   Iron reduced.
§ 582.5381   Isoleucine.
§ 582.5406   Leucine.
§ 582.5411   Lysine.
§ 582.5431   Magnesium oxide.
§ 582.5434   Magnesium phosphate.
§ 582.5443   Magnesium sulfate.
§ 582.5446   Manganese chloride.
§ 582.5449   Manganese citrate.
§ 582.5452   Manganese gluconate.
§ 582.5455   Manganese glycerophosphate.
§ 582.5458   Manganese hypophosphite.
§ 582.5461   Manganese sulfate.
§ 582.5464   Manganous oxide.
§ 582.5470   Mannitol.
§ 582.5475   Methionine.
§ 582.5477   Methionine hydroxy analog and its calcium salts.
§ 582.5530   Niacin.
§ 582.5535   Niacinamide.
§ 582.5580   D-Pantothenyl alcohol.
§ 582.5590   Phenylalanine.
§ 582.5622   Potassium chloride.
§ 582.5628   Potassium glycerophosphate.
§ 582.5634   Potassium iodide.
§ 582.5650   Proline.
§ 582.5676   Pyridoxine hydrochloride.
§ 582.5695   Riboflavin.
§ 582.5697   Riboflavin-5-phosphate.
§ 582.5701   Serine.
§ 582.5772   Sodium pantothenate.
§ 582.5778   Sodium phosphate.
§ 582.5835   Sorbitol.
§ 582.5875   Thiamine hydrochloride.
§ 582.5878   Thiamine mononitrate.
§ 582.5881   Threonine.
§ 582.5890   Tocopherols.
§ 582.5892   a-Tocopherol acetate.
§ 582.5915   Tryptophane.
§ 582.5920   Tyrosine.
§ 582.5925   Valine.
§ 582.5930   Vitamin A.
§ 582.5933   Vitamin A acetate.
§ 582.5936   Vitamin A palmitate.
§ 582.5945   Vitamin B12.
§ 582.5950   Vitamin D2.
§ 582.5953   Vitamin D3.
§ 582.5985   Zinc chloride.
§ 582.5988   Zinc gluconate.
§ 582.5991   Zinc oxide.
§ 582.5994   Zinc stearate.
§ 582.5997   Zinc sulfate.

Subpart G—Sequestrants2

§ 582.6033   Citric acid.
§ 582.6085   Sodium acid phosphate.
§ 582.6099   Tartaric acid.
§ 582.6185   Calcium acetate.
§ 582.6193   Calcium chloride.
§ 582.6195   Calcium citrate.
§ 582.6197   Calcium diacetate.
§ 582.6199   Calcium gluconate.
§ 582.6203   Calcium hexametaphosphate.
§ 582.6215   Monobasic calcium phosphate.
§ 582.6219   Calcium phytate.
§ 582.6285   Dipotassium phosphate.
§ 582.6290   Disodium phosphate.
§ 582.6386   Isopropyl citrate.
§ 582.6511   Monoisopropyl citrate.
§ 582.6625   Potassium citrate.
§ 582.6751   Sodium citrate.
§ 582.6754   Sodium diacetate.
§ 582.6757   Sodium gluconate.
§ 582.6760   Sodium hexametaphosphate.
§ 582.6769   Sodium metaphosphate.
§ 582.6778   Sodium phosphate.
§ 582.6787   Sodium pyrophosphate.
§ 582.6789   Tetra sodium pyrophosphate.
§ 582.6801   Sodium tartrate.
§ 582.6804   Sodium potassium tartrate.
§ 582.6807   Sodium thiosulfate.
§ 582.6810   Sodium tripolyphosphate.
§ 582.6851   Stearyl citrate.

Subpart H—Stabilizers

§ 582.7115   Agar-agar.
§ 582.7133   Ammonium alginate.
§ 582.7187   Calcium alginate.
§ 582.7255   Chondrus extract.
§ 582.7330   Gum arabic.
§ 582.7333   Gum ghatti.
§ 582.7339   Guar gum.
§ 582.7343   Locust bean gum.
§ 582.7349   Sterculia gum.
§ 582.7351   Gum tragacanth.
§ 582.7610   Potassium alginate.
§ 582.7724   Sodium alginate.

Authority:  21 U.S.C. 321, 342, 348, 371.

Source:  41 FR 38657, Sept. 10, 1976, unless otherwise noted.

Subpart A—General Provisions
top
§ 582.1   Substances that are generally recognized as safe.
 top

(a) It is impracticable to list all substances that are generally recognized as safe for their intended use. However, by way of illustration, the Commissioner regards such common food ingredients as salt, pepper, sugar, vinegar, baking powder, and monosodium glutamate as safe for their intended use. The lists in subparts B through H of this part include additional substances that, when used for the purposes indicated, in accordance with good manufacturing or feeding practice, are regarded by the Commissioner as generally recognized as safe for such uses.

(b) For the purposes of this section, good manufacturing or feeding practice shall be defined to include the following restrictions:

(1) The quantity of a substance added to animal food does not exceed the amount reasonably required to accomplish its intended physical, nutritional, or other technical effect in food; and

(2) The quantity of a substance that becomes a component of animal food as a result of its use in the manufacturing, processing, or packaging of food, and which is not intended to accomplish any physical or other technical effect in the food itself, shall be reduced to the extent reasonably possible.

(3) The substance is of appropriate grade and is prepared and handled as a food ingredient. Upon request the Commissioner will offer an opinion, based on specifications and intended use, as to whether or not a particular grade or lot of the substance is of suitable purity for use in food and would generally be regarded as safe for the purpose intended, by experts qualified to evaluate its safety.

(c) The inclusion of substances in the list of nutrients does not constitute a finding on the part of the Department that the substance is useful as a supplement to the diet for animals.

(d) Substances that are generally recognized as safe for their intended use within the meaning of section 409 of the Act are listed in subparts B through H of this part. When the status of a substance has been reevaluated and affirmed as GRAS or deleted from subparts B through H of this part, an appropriate explanation will be noted, e.g., “affirmed as GRAS,” “food additive regulation,” “interim food additive regulation,” or “prohibited from use in food,” with a reference to the appropriate new regulation. Such notation will apply only to the specific use covered by the review, e.g., direct animal food use and/or indirect animal food use and/or animal feed use and will not affect its status for other uses not specified in the referenced regulation, pending a specific review of such other uses.

§ 582.10   Spices and other natural seasonings and flavorings.
 top

Spices and other natural seasonings and flavorings that are generally recognized as safe for their intended use, within the meaning of section 409 of the act, are as follows:

 ------------------------------------------------------------------------              Common name                 Botanical name of plant source------------------------------------------------------------------------Alfalfa herb and seed..................  Medicago sativa L.Allspice...............................  Pimenta officinalis Lindl.Ambrette seed..........................  Hibiscus abelmoschus L.Angelica...............................  Angelica archangelica L. or                                          other spp. of Angelica.Angelica root..........................   Do.Angelica seed..........................   Do.Angostura (cusparia bark)..............  Galipea officinalis Hancock.Anise..................................  Pimpinella anisum L.Anise, star............................  Illicium verum Hook. f.Balm (lemon balm)......................  Melissa officinalis L.Basil, bush............................  Ocimum minimum L.Basil, sweet...........................  Ocimum basilicum L.Bay....................................  Laurus nobilis L.Calendula..............................  Calendula officinalis L.Camomile (chamomile), English or Roman.  Anthemis nobilis L.Camomile (chamomile), German or          Matricaria chamomilla L. Hungarian.Capers.................................  Capparis spinosa L.Capsicum...............................  Capsicum frutescens L. or                                          Capsicum annuum L.Caraway................................  Carum carvi L.Caraway, black (black cumin)...........  Nigella sativa L.Cardamom (cardamon)....................  Elettaria cardamomum Maton.Cassia, Chinese........................  Cinnamomum cassia Blume.Cassia, Padang or Batavia..............  Cinnamomum burmanni Blume.Cassia, Saigon.........................  Cinnamomum loureirii Nees.Cayenne pepper.........................  Capsicum frutescens L. or                                          Capsicum annuum L.Celery seed............................  Apium graveolens L.Chervil................................  Anthriscus cerefolium (L.)                                          Hoffm.Chives.................................  Allium schoenoprasum L.Cinnamon, Ceylon.......................  Cinnamomum zeylanicum Nees.Cinnamon, Chinese......................  Cinnamomum cassia Blume.Cinnamon, Saigon.......................  Cinnamomum loureirii Nees.Clary (clary sage).....................  Salvia sclarea L.Clover.................................  Trifolium spp.Cloves.................................  Eugenia caryophyllata Thunb.Coriander..............................  Coriandrum sativum L.Cumin (cummin).........................  Cuminum cyminum L.Cumin, black (black caraway)...........  Nigella sativa L.Dill...................................  Anethum graveolens L.Elder flowers..........................  Sambucus canadensis L.Fennel, common.........................  Foeniculum vulgare Mill.Fennel, sweet (finocchio, Florence       Foeniculum vulgare Mill. var. fennel).                                 duice (DC.) Alex.Fenugreek..............................  Trigonella foenum-graecum L.Galanga (galangal).....................  Alpina officinarum Hance.Garlic.................................  Allium sativum L.Geranium...............................  Pelargonium spp.Ginger.................................  Zingiber officinale Rosc.Glycyrrhiza............................  Glycyrrhiza glabra L. and other                                          spp. of Glycyrrhiza.Grains of paradise.....................  Amomum melegueta Rosc.Horehound (hoarhound)..................  Marrubium vulgare L.Horseradish............................  Armoracia lapathifolia Gilib.Hyssop.................................  Hyssopus officinalis L.Lavender...............................  Lavandula officinalis Chaix.Licorice...............................  Glycyrrhiza glabra L. and other                                          spp. of Glycyrrhiza.Linden flowers.........................  Tilia spp.Mace...................................  Myristica fragrans Houtt.Marigold, pot..........................  Calendula officinalis L.Marjoram, pot..........................  Majorana onites (L.) Benth.Marjoram, sweet........................  Majorana hortensis Moench.Mustard, black or brown................  Brassica nigra (L.) Koch.Mustard, brown.........................  Brassica juncea (L.) Coss.Mustard, white or yellow...............  Brassica hirta Moench.Nutmeg.................................  Myristica fragrans Houtt.Oregano (oreganum, Mexican oregano,      Lippia spp. Mexican sage, origan).Paprika................................  Capsicum annuum L.Parsley................................  Petroselinum crispum (Mill.)                                          Mansf.Pepper, black..........................  Piper nigrum L.Pepper, cayenne........................  Capsicum frutescens L. or                                          Capsicum annuum L.Pepper, red............................   Do.Pepper, white..........................  Piper nigrum L.Peppermint.............................  Mentha piperita L.Poppy seed.............................  Papaver somniferum L.Pot marigold...........................  Calendula officinalis L.Pot marjoram...........................  Majorana onites (L.) Benth.Rosemary...............................  Rosmarinus officinalis L.Rue....................................  Ruta graveolens L.Saffron................................  Crocus sativus L.Sage...................................  Salvia officinalis L.Sage, Greek............................  Salvia triloba L.Savory, summer.........................  Satureia hortensis L.                                          (Satureja).Savory, winter.........................  Satureia montana L. (Satureja).Sesame.................................  Sesamum indicum L.Spearmint..............................  Mentha spicata L.Star anise.............................  Illicium verum Hook. f.Tarragon...............................  Artemisia dracunculus L.Thyme..................................  Thymus vulgaris L.Thyme, wild or creeping................  Thymus serpyllum L.Turmeric...............................  Curcuma longa L.Vanilla................................  Vanilla planifolia Andr. or                                          Vanilla tahitensis J. W.                                          Moore.Zedoary................................  Curcuma zedoaria Rosc.------------------------------------------------------------------------
§ 582.20   Essential oils, oleoresins (solvent-free), and natural extractives (including distillates).
 top

Essential oils, oleoresins (solvent-free), and natural extractives (including distillates) that are generally recognized as safe for their intended use, within the meaning of section 409 of the act, are as follows:

 
 ------------------------------------------------------------------------              Common name                 Botanical name of plant source------------------------------------------------------------------------Alfalfa................................  Medicago sativa L.Allspice...............................  Pimenta officinalis Lindl.Almond, bitter (free from prussic acid)  Prunus amygdalus Batsch, Prunus                                          armeniaca L. or Prunus persica                                          (L.) Batsch.Ambrette (seed)........................  Hibiscus moschatus Moench.Angelica root..........................  Angelica archangelica L.Angelica seed..........................   Do.Angelica stem..........................   Do.Angostura (cusparia bark)..............  Galipea officinalis Hancock.Anise..................................  Pimpinella anisum L.Asafetida..............................  Ferula assa-foetida L. and                                          related spp. of Ferula.Balm (lemon balm)......................  Melissa officinalis L.Balsam of Peru.........................  Myroxylon pereirae Klotzsch.Basil..................................  Ocimum basilicum L.Bay leaves.............................  Laurus nobilis L.Bay (myrcia oil).......................  Pimenta racemosa (Mill.) J. W.                                          Moore.Bergamot (bergamot orange).............  Citrus aurantium L. subsp.                                          bergamia Wright et Arn.Bitter almond (free from prussic acid).  Prunus amygdalus Batsch, Prunus                                          armeniaca L., or Prunus                                          persica (L.) Batsch.Bois de rose...........................  Aniba rosaeodora Ducke.Cacao..................................  Theobroma cacao L.Camomile (chamomile) flowers, Hungarian  Matricaria chamomilla L.Camomile (chamomile) flowers, Roman or   Anthemis nobilis L. English.Cananga................................  Cananga odorata Hook. f. and                                          Thoms.Capsicum...............................  Capsicum frutescens L. and                                          Capsicum annuum L.Caraway................................  Carum carvi L.Cardamom seed (cardamon)...............  Elettaria cardamomum Maton.Carob bean.............................  Ceratonia siliqua L.Carrot.................................  Daucus carota L.Cascarilla bark........................  Croton eluteria Benn.Cassia bark, Chinese...................  Cinnamomum cassia Blume.Cassia bark, Padang or Batavia.........  Cinnamomum burmanni Blume.Cassia bark, Saigon....................  Cinnamomum loureirii Nees.Celery seed............................  Apium graveolens L.Cherry, wild, bark.....................  Prunus serotina Ehrh.Chervil................................  Anthriscus cerefolium (L.)                                          Hoffm.Chicory................................  Cichorium intybus L.Cinnamon bark, Ceylon..................  Cinnamomum zeylanicum Nees.Cinnamon bark, Chinese.................  Cinnamomum cassia Blume.Cinnamon bark, Saigon..................  Cinnamomum loureirii Nees.Cinnamon leaf, Ceylon..................  Cinnamomum zeylanicum Nees.Cinnamon leaf, Chinese.................  Cinnamomum cassia Blume.Cinnamon leaf, Saigon..................  Cinnamomum loureirii Nees.Citronella.............................  Cymbopogon nardus Rendle.Citrus peels...........................  Citrus spp.Clary (clary sage).....................  Salvia sclarea L.Clove bud..............................  Eugenia caryophyllata Thunb.Clove leaf.............................   Do.Clove stem.............................   Do.Clover.................................  Trifolium spp.Coca (decocainized)....................  Erythroxylum coca Lam. and                                          other spp. of Erythroxylum.Coffee.................................  Coffea spp.Cola nut...............................  Cola acuminata Schott and                                          Endl., and other spp. of Cola.Coriander..............................  Coriandrum sativum L.Corn silk..............................  Zea mays L.Cumin (cummin).........................  Cuminum cyminum L.Curacao orange peel (orange, bitter      Citrus aurantium L. peel).Cusparia bark..........................  Galipea officinalis Hancock.Dandelion..............................  Taraxacum officinale Weber and                                          T. laevigatum DC.Dandelion root.........................   Do.Dill...................................  Anethum graveolens L.Dog grass (quackgrass, triticum).......  Agropyron repens (L.) Beauv.Elder flowers..........................  Sambucus canadensis L. and S.                                          nigra L.Estragole (esdragol, esdragon,           Artemisia dracunculus L. tarragon).Estragon (tarragon)....................   Do.Fennel, sweet..........................  Foeniculum vulgare Mill.Fenugreek..............................  Trigonella foenum-graecum L.Galanga (galangal).....................  Alpinia officinarum Hance.Garlic.................................  Allium sativum L.Geranium...............................  Pelargonium spp.Geranium, East Indian..................  Cymbopogon martini Stapf.Geranium, rose.........................  Pelargonium graveolens L'Her.Ginger.................................  Zingiber officinale Rosc.Glycyrrhiza............................  Glycyrrhiza glabra L. and other                                          spp. of Glycyrrhiza.Glycyrrhizin, ammoniated...............   Do.Grapefruit.............................  Citrus paradisi Macf.Guava..................................  Psidium spp.Hickory bark...........................  Carya spp.Horehound (hoarhound)..................  Marrubium vulgare L.Hops...................................  Humulus lupulus L.Horsemint..............................  Monarda punctata L.Hyssop.................................  Hyssopus officinalis L.Immortelle.............................  Helichrysum augustifolium DC.Jasmine................................  Jaminum officinale L. and other                                          spp. of Jasminum.Juniper (berries)......................  Juniperus communis L.Kola nut...............................  Cola acuminata Schott and                                          Endl., and other spp. of Cola.Laurel berries.........................  Laurus nobilis L.Laurel leaves..........................  Laurus spp.Lavender...............................  Lavandula officinalis Chaix.Lavender, spike........................  Lavandula latifolia Vill.Lavandin...............................  Hybrids between Lavandula                                          officinalis Chaix and                                          Lavandula latifolin Vill.Lemon..................................  Citrus limon (L.) Burm. f.Lemon balm (see balm).Lemon grass............................  Cymbopogon citratus DC. and                                          Cymbopogon flexuosus Stapf.Lemon peel.............................  Citrus limon (L.) Burm. f.Licorice...............................  Glycyrrhiza glabra L. and other                                          spp. of Glycyrrhiza.Lime...................................  Citrus aurantifolia Swingle.Linden flowers.........................  Tilia spp.Locust bean............................  Ceratonia siliqua L.Lupulin................................  Humulus lupulus L.Mace...................................  Myristica fragrans Houtt.Malt (extract).........................  Hordeum vulgare L., or other                                          grains.Mandarin...............................  Citrus reticulata Blanco.Marjoram, sweet........................  Majorana hortensis Moench.Mate 1.................................  Ilex paraguariensis St. Hil.Melissa (see balm).Menthol................................  Mentha spp.Menthyl acetate........................   Do.Molasses (extract).....................  Saccharum officinarum L.Mustard................................  Brassica spp.Naringin...............................  Citrus paradisi Macf.Neroli, bigarade.......................  Citrus aurantium L.Nutmeg.................................  Myristica fragrans Houtt.Onion..................................  Allium cepa L.Orange, bitter, flowers................  Citrus aurantium L.Orange, bitter, peel...................   Do.Orange leaf............................  Citrus sinensis (L.) Osbeck.Orange, sweet..........................   Do.Orange, sweet, flowers.................   Do.Orange, sweet, peel....................   Do.Origanum...............................  Origanum spp.Palmarosa..............................  Cymbopogon martini Stapf.Paprika................................  Capsicum annuum L.Parsley................................  Petroselinum crispum (Mill.)                                          Mansf.Pepper, black..........................  Piper nigrum L.Pepper, white..........................  Piper nigrum L.Peppermint.............................  Mentha piperita L.Peruvian balsam........................  Myroxylon pereirae Klotzsch.Petitgrain.............................  Citrus aurantium L.Petitgrain lemon.......................  Citrus limon (L.) Burm. f.Petitgrain mandarin or tangerine.......  Citrus reticulata Blanco.Pimenta................................  Pimenta officinalis Lindl.Pimenta leaf...........................  Primenta officinalis Lindl.Pipsissewa leaves......................  Chimaphila umbellata Nutt.Pomegranate............................  Punica granatum L.Prickly ash bark.......................  Xanthoxylum (or Zanthoxylum)                                          Americanum Mill. or                                          Xanthoxylum clava-herculis L.Rose absolute..........................  Rosa alba L., Rosa centifolia                                          L., Rosa damascena Mill., Rosa                                          gallica L., and vars. of these                                          spp.Rose (otto of roses, attar of roses)...   Do.Rose buds..............................   Do.Rose flowers...........................   Do.Rose fruit (hips)......................   Do.Rose geranium..........................  Pelargonium graveolens L'Her.Rose leaves............................  Rosa spp.Rosemary...............................  Rosmarinus officinalis L.Rue....................................  Ruta graveolens L.Saffron................................  Crocus sativus L.Sage...................................  Salvia officinalis L.Sage, Greek............................  Salvia triloba L.Sage, Spanish..........................  Salvia lavandulaefolia Vahl.St. John's bread.......................  Ceratonia siliqua L.Savory, summer.........................  Satureia hortensis L.Savory, winter.........................  Satureia montana L.Schinus molle..........................  Schinus molle L.Sloe berries (blackthorn berries)......  Prunus spinosa L.Spearmint..............................  Mentha spicata L.Spike lavender.........................  Lavandula latifolia Vill.Tamarind...............................  Tamarindus indica L.Tangerine..............................  Citrus reticulata Blanco.Tannic acid............................  Nutgalls of Quercus infectoria                                          Oliver and related spp. of                                          Quercus. Also in many other                                          plants.Tarragon...............................  Artemisia dracunculus L.Tea....................................  Thea sinensis L.Thyme..................................  Thymus vulgaris L. and Thymus                                          zygis var. gracilis Boiss.Thyme, white...........................   Do.Thyme, wild or creeping................  Thymus serpyllum L.Triticum (see dog grass).Tuberose...............................  Polianthes tuberosa L.Turmeric...............................  Curcuma longa L.Vanilla................................  Vanilla planifolia Andr. or                                          Vanilla tahitensis J. W.                                          Moore.Violet flowers.........................  Viola odorata L.Violet leaves..........................   Do.Violet leaves absolute.................   Do.Wild cherry bark.......................  Prunus serotina Ehrh.Ylang-ylang............................  Cananga odorata Hook. f. and                                          Thoms.Zedoary bark...........................  Curcuma zedoaria Rosc.------------------------------------------------------------------------
§ 582.30   Natural substances used in conjunction with spices and other natural seasonings and flavorings.
 top

Natural substances used in conjunction with spices and other natural seasonings and flavorings that are generally recognized as safe for their intended use, within the meaning of section 409 of the act, are as follows:

 
 ------------------------------------------------------------------------              Common name                 Botanical name of plant source------------------------------------------------------------------------Algae, brown (kelp)....................  Laminaria spp. and Nereocystis                                          spp.Algae, red.............................  Porphyra spp. and Rhodymenia                                          palmata (L.) Grev.Dulse..................................  Rhodymenia palmata (L.)------------------------------------------------------------------------
§ 582.40   Natural extractives (solvent-free) used in conjunction with spices, seasonings, and flavorings.
 top

Natural extractives (solvent-free) used in conjunction with spices, seasonings, and flavorings that are generally recognized as safe for their intended use, within the meaning of section 409 of the act, are as follows:

 
 ------------------------------------------------------------------------              Common name                 Botanical name of plant source------------------------------------------------------------------------Algae, brown...........................  Laminaria spp. and Nereocystis                                          spp.Algae, red.............................  Porphyra spp. and Rhodymenia                                          palmata (L.) Grev.Apricot kernel (persic oil)............  Prunus armeniaca L.Dulse..................................  Rhodymenia palmata (L.) Grev.Kelp (see algae, brown).Peach kernel (persic oil)..............  Prunus persica Sieb. et Zucc.Peanut stearine........................  Arachis hypogaea L.Persic oil (see apricot kernel and peach kernel).Quince seed............................  Cydonia oblonga Miller.------------------------------------------------------------------------
§ 582.50   Certain other spices, seasonings, essential oils, oleoresins, and natural extracts.
 top

Certain other spices, seasonings, essential oils, oleoresins, and natural extracts that are generally recognized as safe for their intended use, within the meaning of section 409 of the act, are as follows:

 
 ------------------------------------------------------------------------              Common name                           Derivation------------------------------------------------------------------------Ambergris..............................  Physeter macrocephalus L.Castoreum..............................  Castor fiber L. and C.                                          canadensis Kuhl.Civet (zibeth, zibet, zibetum).........  Civet cats, Viverra civetta                                          Schreber and Viverra zibetha                                          Schreber.Cognac oil, white and green............  Ethyl oenanthate, so-called.Musk (Tonquin musk)....................  Musk deer, Moschus moschiferus                                          L.------------------------------------------------------------------------
§ 582.60   Synthetic flavoring substances and adjuvants.
 top

Synthetic flavoring substances and adjuvants that are generally recognized as safe for their intended use, within the meaning of section 409 of the act, are as follows:

Acetaldehyde (ethanal).

Acetoin (acetyl methylcarbinol).

Aconitic acid (equisetic acid, citridic acid, achilleic acid).

Anethole (parapropenyl anisole).

Benzaldehyde (benzoic aldehyde).

N-Butyric acid (butanoic acid).

d- or l-Carvone (carvol).

Cinnamaldehyde (cinnamic aldehyde).

Citral (2,6-dimethyloctadien-2,6-al-8, geranial, neral).

Decanal (N-decylaldhehyde, capraldehyde, capric aldehyde, caprinaldehyde, aldehyde C-10).

Diacetyl (2,3-butandeione). Ethyl acetate. Ethyl butyrate.

3-Methyl-3-phenyl glycidic acid ethyl ester (ethyl-methyl-phenyl-glycidate, so-called strawberry aldehyde, C-16 aldehyde).

Ethyl vanillin.

Eugenol.

Geranoil (3,7-dimethyl-2,6 and 3,6-octadien-1-ol).

Geranyl acetate (geraniol acetate).

Glycerol (glyceryl) tributyrate (tributyrin, butyrin).

Limonene (d-, l-, and dl-).

Linalool (linalol, 3,7-dimethyl-1,6-octadien-3-ol).

Linalyl acetate (bergamol).

1-Malic acid.

Methyl anthranilate (methyl-2-aminobenzoate).

Piperonal (3,4-methylenedioxy-benzaldehyde, heliotropin).

Vanillin.

§ 582.80   Trace minerals added to animal feeds.
 top

These substances added to animal feeds as nutritional dietary supplements are generally recognized as safe when added at levels consistent with good feeding practice.1

1 All substances listed may be in anhydrous or hydrated form.

 
 ------------------------------------------------------------------------                Element                         Source compounds------------------------------------------------------------------------Cobalt................................  Cobalt acetate.                                        Cobalt carbonate.                                        Cobalt chloride.                                        Cobalt oxide.                                        Cobalt sulfate.Copper................................  Copper carbonate.                                        Copper chloride.                                        Copper gluconate.                                        Copper hydroxide.                                        Copper orthophosphate.                                        Copper oxide.                                        Copper pyrophosphate.                                        Copper sulfate.Iodine................................  Calcium iodate.                                        Calcium iodobehenate.                                        Cuprous iodide.                                        3,5-Diiodosalicylic acid.                                        Ethylenediamine dihydroiodide.                                        Potassium iodate.                                        Potassium iodide.                                        Sodium iodate.                                        Sodium iodide.                                        Thymol iodide.Iron..................................  Iron ammonium citrate.                                        Iron carbonate.                                        Iron chloride.                                        Iron gluconate.                                        Iron oxide.                                        Iron phosphate.                                        Iron pyrophosphate.                                        Iron sulfate.                                        Reduced iron.Manganese.............................  Manganese acetate.                                        Manganese carbonate.                                        Manganese citrate (soluble).                                        Manganese chloride.                                        Manganese gluconate.                                        Manganese orthophosphate.                                        Manganese phosphate (dibasic).                                        Manganese sulfate.                                        Manganous oxide.Zinc..................................  Zinc acetate.                                        Zinc carbonate.                                        Zinc chloride.                                        Zinc oxide.                                        Zinc sulfate.------------------------------------------------------------------------
§ 582.99   Adjuvants for pesticide chemicals.
 top

Adjuvants, identified and used in accordance with 40 CFR 180.1001(c) and (d), which are added to pesticide use dilutions by a grower or applicator prior to application to the raw agricultural commodity, are exempt from the requirement of tolerances under section 409 of the act.

Subpart B—General Purpose Food Additives
 top
§ 582.1005   Acetic acid.
 top

(a) Product. Acetic acid.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1009   Adipic acid.
 top

(a) Product. Adipic acid.

(b) [Reserved]

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used as a buffer and neutralizing agent in accordance with good manufacturing or feeding practice.

§ 582.1033   Citric acid.
 top

(a) Product. Citric acid.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1057   Hydrochloric acid.
 top

(a) Product. Hydrochloric acid.

(b) [Reserved]

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used as a buffer and neutralizing agent in accordance with good manufacturing or feeding practice.

§ 582.1061   Lactic acid.
 top

(a) Product. Lactic acid.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1069   Malic acid.
 top

(a) Product. Malic acid.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1073   Phosphoric acid.
 top

(a) Product. Phosphoric acid.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1077   Potassium acid tartrate.
 top

(a) Product. Potassium acid tartrate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1087   Sodium acid pyrophosphate.
 top

(a) Product. Sodium acid pyrophosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1091   Succinic acid.
 top

(a) Product. Succinic acid.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1095   Sulfuric acid.
 top

(a) Product. Sulfuric acid.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1099   Tartaric acid.
 top

(a) Product. Tartaric acid.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1125   Aluminum sulfate.
 top

(a) Product. Aluminum sulfate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1127   Aluminum ammonium sulfate.
 top

(a) Product. Aluminum ammonium sulfate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1129   Aluminum potassium sulfate.
 top

(a) Product. Aluminum potassium sulfate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1131   Aluminum sodium sulfate.
 top

(a) Product. Aluminum sodium sulfate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1135   Ammonium bicarbonate.
 top

(a) Product. Ammonium bicarbonate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1137   Ammonium carbonate.
 top

(a) Product. Ammonium carbonate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1139   Ammonium hydroxide.
 top

(a) Product. Ammonium hydroxide.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1141   Ammonium phosphate.
 top

(a) Product. Ammonium phosphate (mono- and dibasic).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1143   Ammonium sulfate.
 top

(a) Product. Ammonium sulfate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1155   Bentonite.
 top

(a) Product. Bentonite.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1165   Butane.
 top

(a) Product. Butane.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1191   Calcium carbonate.
 top

(a) Product. Calcium carbonate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1193   Calcium chloride.
 top

(a) Product. Calcium chloride.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1195   Calcium citrate.
 top

(a) Product. Calcium citrate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1199   Calcium gluconate.
 top

(a) Product. Calcium gluconate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1205   Calcium hydroxide.
 top

(a) Product. Calcium hydroxide.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1207   Calcium lactate.
 top

(a) Product. Calcium lactate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1210   Calcium oxide.
 top

(a) Product. Calcium oxide.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1217   Calcium phosphate.
 top

(a) Product. Calcium phosphate (mono-, di-, and tribasic).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1235   Caramel.
 top

(a) Product. Caramel.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1240   Carbon dioxide.
 top

(a) Product. Carbon dioxide.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1275   Dextrans.
 top

(a) Product. Dextrans of average molecular weight below 100,000.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1320   Glycerin.
 top

(a) Product. Glycerin.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1324   Glyceryl monostearate.
 top

(a) Product. Glyceryl monostearate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1355   Helium.
 top

(a) Product. Helium.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1366   Hydrogen peroxide.
 top

(a) Product. Hydrogen peroxide.

(b) [Reserved]

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used as a bleaching agent in accordance with good manufacturing or feeding practice.

§ 582.1400   Lecithin.
 top

(a) Product. Lecithin.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1425   Magnesium carbonate.
 top

(a) Product. Magnesium carbonate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1428   Magnesium hydroxide.
 top

(a) Product. Magnesium hydroxide.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1431   Magnesium oxide.
 top

(a) Product. Magnesium oxide.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1480   Methylcellulose.
 top

(a) Product. U.S.P. methylcellulose, except that the methoxy content shall not be less than 27.5 percent and not more than 31.5 percent on a dry-weight basis.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1500   Monoammonium glutamate.
 top

(a) Product. Monoammonium glutamate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1516   Monopotassium glutamate.
 top

(a) Product. Monopotassium glutamate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1540   Nitrogen.
 top

(a) Product. Nitrogen.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1585   Papain.
 top

(a) Product. Papain.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1613   Potassium bicarbonate.
 top

(a) Product. Potassium bicarbonate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1619   Potassium carbonate.
 top

(a) Product. Potassium carbonate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1625   Potassium citrate.
 top

(a) Product. Potassium citrate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1631   Potassium hydroxide.
 top

(a) Product. Potassium hydroxide.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1643   Potassium sulfate.
 top

(a) Product. Potassium sulfate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1655   Propane.
 top

(a) Product. Propane.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1666   Propylene glycol.
 top

(a) Product. Propylene glycol.

(b) Conditions of use. This substance is generally recognized as safe (except in cat food) when used in accordance with good manufacturing or feeding practice.

[41 FR 38657, Sept. 10, 1976, as amended at 61 FR 19544, May 2, 1996]

§ 582.1685   Rennet.
 top

(a) Product. Rennet (rennin).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1711   Silica aerogel.
 top

(a) Product. Silica aerogel as a finely powdered microcellular silica foam having a minimum silica content of 89.5 percent.

(b) [Reserved]

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used as a component of antifoaming agents in accordance with good manufacturing or feeding practice.

§ 582.1721   Sodium acetate.
 top

(a) Product. Sodium acetate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1736   Sodium bicarbonate.
 top

(a) Product. Sodium bicarbonate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1742   Sodium carbonate.
 top

(a) Product. Sodium carbonate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1745   Sodium carboxymethylcellulose.
 top

(a) Product. Sodium carboxymethyl- cellulose is the sodium salt of carboxymethylcellulose not less than 99.5 percent on a dry-weight basis, with maximum substitution of 0.95 carboxymethyl groups per anhydroglucose unit, and with a minimum viscosity of 25 centipoises for 2 percent by weight aqueous solution at 25 °C.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1748   Sodium caseinate.
 top

(a) Product. Sodium caseinate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1751   Sodium citrate.
 top

(a) Product. Sodium citrate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1763   Sodium hydroxide.
 top

(a) Product. Sodium hydroxide.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1775   Sodium pectinate.
 top

(a) Product. Sodium pectinate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1778   Sodium phosphate.
 top

(a) Product. Sodium phosphate (mono-, di-, and tribasic).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1781   Sodium aluminum phosphate.
 top

(a) Product. Sodium aluminum phosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1792   Sodium sesquicarbonate.
 top

(a) Product. Sodium sesquicarbonate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1804   Sodium potassium tartrate.
 top

(a) Product. Sodium potassium tartrate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1810   Sodium tripolyphosphate.
 top

(a) Product. Sodium tripolyphosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1901   Triacetin.
 top

(a) Product. Triacetin (glyceryl triacetate).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1973   Beeswax.
 top

(a) Product. Beeswax (yellow wax).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1975   Bleached beeswax.
 top

(a) Product. Bleached beeswax (white wax).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1978   Carnauba wax.
 top

(a) Product. Carnauba wax.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

Subpart C—Anticaking Agents
 top
§ 582.2122   Aluminum calcium silicate.
 top

(a) Product. Aluminum calcium silicate.

(b) Tolerance. 2 percent.

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in table salt in accordance with good manufacturing or feeding practice.

§ 582.2227   Calcium silicate.
 top

(a) Product. Calcium silicate.

(b) Tolerance. 2 percent and 5 percent.

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used at levels not exceeding 2 percent in table salt and 5 percent in baking powder in accordance with good manufacturing or feeding practice.

§ 582.2437   Magnesium silicate.
 top

(a) Product. Magnesium silicate.

(b) Tolerance. 2 percent.

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in table salt in accordance with good manufacturing or feeding practice.

§ 582.2727   Sodium aluminosilicate.
 top

(a) Product. Sodium aluminosilicate (sodium silicoaluminate).

(b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 2 percent in accordance with good manufacturing or feeding practice.

§ 582.2729   Hydrated sodium calcium aluminosilicate.
 top

(a) Product. Hydrated sodium calcium aluminosilicate (sodium calcium silicoaluminate).

(b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 2 percent in accordance with good manufacturing or feeding practice.

§ 582.2906   Tricalcium silicate.
 top

(a) Product. Tricalcium silicate.

(b) Tolerance. 2 percent.

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in table salt in accordance with good manufacturing or feeding practice.

Subpart D—Chemical Preservatives
 top
§ 582.3013   Ascorbic acid.
 top

(a) Product. Ascorbic acid.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.3021   Benzoic acid.
 top

(a) Product. Benzoic acid.

(b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 0.1 percent in accordance with good manufacturing or feeding practice.

§ 582.3041   Erythorbic acid.
 top

(a) Product. Erythorbic acid.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.3081   Propionic acid.
 top

(a) Product. Propionic acid.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.3089   Sorbic acid.
 top

(a) Product. Sorbic acid.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.3109   Thiodipropionic acid.
 top

(a) Product. Thiodipropionic acid.

(b) Tolerance. This substance is generally recognized as safe for use in food when the total content of antioxidants is not over 0.02 percent of fat or oil content including essential (volatile) oil content of the food, provided the substance is used in accordance with good manufacturing or feeding practice.

§ 582.3149   Ascorbyl palmitate.
 top

(a) Product. Ascorbyl palmitate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.3169   Butylated hydroxyanisole.
 top

(a) Product. Butylated hydroxyanisole.

(b) Tolerance. This substance is generally recognized as safe for use in food when the total content of antioxidants is not over 0.02 percent of fat or oil content, including essential (volatile) oil content of food provided the substance is used in accordance with good manufacturing or feeding practice.

§ 582.3173   Butylated hydroxytoluene.
 top

(a) Product. Butylated hydroxytol- uene.

(b) Tolerance. This substance is generally recognized as safe for use in food when the total content of antioxidants is not over 0.02 percent of fat or oil content, including essential (volatile) oil content of food provided the substance is used in accordance with good manufacturing or feeding practice.

§ 582.3189   Calcium ascorbate.
 top

(a) Product. Calcium ascorbate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.3221   Calcium propionate.
 top

(a) Product. Calcium propionate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.3225   Calcium sorbate.
 top

(a) Product. Calcium sorbate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.3280   Dilauryl thiodipropionate.
 top

(a) Product. Dilauryl thiodipropionate.

(b) Tolerance. This substance is generally recognized as safe for use in food when the total content of antioxidants is not over 0.02 percent of fat or oil content, including essential (volatile) oil content of the food, provided the substance is used in accordance with good manufacturing or feeding practice.

§ 582.3336   Gum guaiac.
 top

(a) Product. Gum guaiac.

(b) Tolerance. 0.1 percent (equivalent antioxidant activity 0.01 percent).

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in edible fats or oils in accordance with good manufacturing or feeding practice.

§ 582.3490   Methylparaben.
 top

(a) Product. Methylparaben (methyl p-hydroxybenzoate).

(b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 0.1 percent in accordance with good manufacturing or feeding practice.

§ 582.3616   Potassium bisulfite.
 top

(a) Product. Potassium bisulfite.

(b) [Reserved]

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice, except that it is not used in meats or in food recognized as source of vitamin B1.

§ 582.3637   Potassium metabisulfite.
 top

(a) Product. Potassium metabisulfite.

(b) [Reserved]

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice, except that it is not used in meats or in food recognized as source of vitamin B1.

§ 582.3640   Potassium sorbate.
 top

(a) Product. Potassium sorbate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.3660   Propyl gallate.
 top

(a) Product. Propyl gallate.

(b) Tolerance. This substance is generally recognized as safe for use in food when the total content of antioxidants is not over 0.02 percent of fat or oil content, including essential (volatile) oil content of the food, provided the substance is used in accordance with good manufacturing or feeding practice.

§ 582.3670   Propylparaben.
 top

(a) Product. Propylparaben (propyl p-hydroxybenzoate).

(b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 0.1 percent in accordance with good manufacturing or feeding practice.

§ 582.3731   Sodium ascorbate.
 top

(a) Product. Sodium ascorbate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.3733   Sodium benzoate.
 top

(a) Product. Sodium benzoate.

(b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 0.1 percent in accordance with good manufacturing or feeding practice.

§ 582.3739   Sodium bisulfite.
 top

(a) Product. Sodium bisulfite.

(b) [Reserved]

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice, except that it is not used in meats or in food recognized as source of vitamin B1.

§ 582.3766   Sodium metabisulfite.
 top

(a) Product. Sodium metabisulfite.

(b) [Reserved]

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice, except that it is not used in meats or in food recognized as source of vitamin B1.

§ 582.3784   Sodium propionate.
 top

(a) Product. Sodium propionate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.3795   Sodium sorbate.
 top

(a) Product. Sodium sorbate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.3798   Sodium sulfite.
 top

(a) Product. Sodium sulfite.

(b) [Reserved]

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice, except that it is not used in meats or in food recognized as source of vitamin B1.

§ 582.3845   Stannous chloride.
 top

(a) Product. Stannous chloride.

(b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 0.0015 percent calculated as tin in accordance with good manufacturing or feeding practice.

§ 582.3862   Sulfur dioxide.
 top

(a) Product. Sulfur dioxide.

(b) [Reserved]

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice, except that it is not used in meats or in food recognized as source of vitamin B1.

§ 582.3890   Tocopherols.
 top

(a) Product. Tocopherols.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

Subpart E—Emulsifying Agents
 top
§ 582.4101   Diacetyl tartaric acid esters of mono- and diglycerides of edible fats or oils, or edible fat-forming fatty acids.
 top

(a) Product. Diacetyl tartaric acid esters of mono- and diglycerides of edible fats or oils, or edible fat-forming fatty acids.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.4505   Mono- and diglycerides of edible fats or oils, or edible fat-forming acids.
 top

(a) Product. Mono- and diglycerides of edible fats or oils, or edible fat-forming acids.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.4521   Monosodium phosphate derivatives of mono- and diglycerides of edible fats or oils, or edible fat-forming fatty acids.
 top

(a) Product. Monosodium phosphate derivatives of mono- and diglycerides of edible fats or oils, or edible fat-forming fatty acids.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.4666   Propylene glycol.
 top

(a) Product. Propylene glycol.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

Subpart F—Nutrients and/or Dietary Supplements1
top
§ 582.5013   Ascorbic acid.
 top

(a) Product. Ascorbic acid.

1 Amino acids listed in this subpart may be free hydrochloride salt, hydrated, or anhydrous form, where applicable.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5017   Aspartic acid.
 top

(a) Product. Aspartic acid (L- and DL-forms).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5049   Aminoacetic acid.
 top

(a) Product. Glycine (aminoacetic acid).

(b) [Reserved]

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in animal feeds in accordance with good manufacturing or feeding practice.

§ 582.5065   Linoleic acid.
 top

(a) Product. Linoleic acid prepared from edible fats and oils and free from chick-edema factor.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5118   Alanine.
 top

(a) Product. Alanine (L- and DL-forms).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5145   Arginine.
 top

(a) Product. Arginine (L- and DL-forms).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5159   Biotin.
 top

(a) Product. Biotin.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5191   Calcium carbonate.
 top

(a) Product. Calcium carbonate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5195   Calcium citrate.
 top

(a) Product. Calcium citrate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5201   Calcium glycerophosphate.
 top

(a) Product. Calcium glycerophosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5210   Calcium oxide.
 top

(a) Product. Calcium oxide.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5212   Calcium pantothenate.
 top

(a) Product. Calcium pantothenate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5217   Calcium phosphate.
 top

(a) Product. Calcium phosphate (mono-, di-, and tribasic).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5223   Calcium pyrophosphate.
 top

(a) Product. Calcium pyrophosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5230   Calcium sulfate.
 top

(a) Product. Calcium sulfate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5245   Carotene.
 top

(a) Product. Carotene.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5250   Choline bitartrate.
 top

(a) Product. Choline bitartrate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5252   Choline chloride.
 top

(a) Product. Choline chloride.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5260   Copper gluconate.
 top

(a) Product. Copper gluconate.

(b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 0.005 percent in accordance with good manufacturing or feeding practice.

§ 582.5271   Cysteine.
 top

(a) Product. Cysteine (L-forms).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5273   Cystine.
 top

(a) Product. Cystine (L- and DL-forms).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5301   Ferric phosphate.
 top

(a) Product. Ferric phosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5304   Ferric pyrophosphate.
 top

(a) Product. Ferric pyrophosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5306   Ferric sodium pyrophosphate.
 top

(a) Product. Ferric sodium pyrophosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5308   Ferrous gluconate.
 top

(a) Product. Ferrous gluconate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5311   Ferrous lactate.
 top

(a) Product. Ferrous lactate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5315   Ferrous sulfate.
 top

(a) Product. Ferrous sulfate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5361   Histidine.
 top

(a) Product. Histidine (L- and DL-forms).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5370   Inositol.
 top

(a) Product. Inositol.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5375   Iron reduced.
 top

(a) Product. Iron reduced.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5381   Isoleucine.
 top

(a) Product. Isoleucine (L- and DL-forms).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5406   Leucine.
 top

(a) Product. Leucine (L- and DL-forms).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5411   Lysine.
 top

(a) Product. Lysine (L- and DL-forms).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5431   Magnesium oxide.
 top

(a) Product. Magnesium oxide.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5434   Magnesium phosphate.
 top

(a) Product. Magnesium phosphate (di- and tribasic).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5443   Magnesium sulfate.
 top

(a) Product. Magnesium sulfate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5446   Manganese chloride.
 top

(a) Product. Manganese chloride.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5449   Manganese citrate.
 top

(a) Product. Manganese citrate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5452   Manganese gluconate.
 top

(a) Product. Manganese gluconate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5455   Manganese glycerophosphate.
 top

(a) Product. Manganese glycerophosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5458   Manganese hypophosphite.
 top

(a) Product. Manganese hypophosphite.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5461   Manganese sulfate.
 top

(a) Product. Manganese sulfate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5464   Manganous oxide.
 top

(a) Product. Manganous oxide.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5470   Mannitol.
 top

(a) Product. Mannitol.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5475   Methionine.
 top

(a) Product. Methionine.

(b) [Reserved]

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in animal feeds in accordance with good manufacturing or feeding practice.

§ 582.5477   Methionine hydroxy analog and its calcium salts.
 top

(a) Product. Methionine hydroxy analog and its calcium salts.

(b) [Reserved]

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in animal feeds in accordance with good manufacturing or feeding practice.

§ 582.5530   Niacin.
 top

(a) Product. Niacin.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5535   Niacinamide.
 top

(a) Product. Niacinamide.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5580   D-Pantothenyl alcohol.
 top

(a) Product. D-Pantothenyl alcohol.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5590   Phenylalanine.
 top

(a) Product. Phenylalanine (L- and DL-forms).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5622   Potassium chloride.
 top

(a) Product. Potassium chloride.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5628   Potassium glycerophosphate.
 top

(a) Product. Potassium glycerophosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5634   Potassium iodide.
 top

(a) Product. Potassium iodide.

(b) Tolerance. 0.01 percent.

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in table salt as a source of dietary iodine in accordance with good manufacturing or feeding practice.

§ 582.5650   Proline.
 top

(a) Product. Proline (L- and DL-forms).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5676   Pyridoxine hydrochloride.
 top

(a) Product. Pyridoxine hydrochloride.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5695   Riboflavin.
 top

(a) Product. Riboflavin.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5697   Riboflavin-5-phosphate.
 top

(a) Product. Riboflavin-5-phosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5701   Serine.
 top

(a) Product. Serine (L- and DL-forms).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5772   Sodium pantothenate.
 top

(a) Product. Sodium pantothenate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5778   Sodium phosphate.
 top

(a) Product. Sodium phosphate (mono-, di-, and tribasic).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5835   Sorbitol.
 top

(a) Product. Sorbitol.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5875   Thiamine hydrochloride.
 top

(a) Product. Thiamine hydrochloride.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5878   Thiamine mononitrate.
 top

(a) Product. Thiamine mononitrate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5881   Threonine.
 top

(a) Product. Threonine (L- and DL-forms).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5890   Tocopherols.
 top

(a) Product. Tocopherols.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5892   a-Tocopherol acetate.
 top

(a) Product. a-Tocopherol acetate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5915   Tryptophane.
 top

(a) Product. Tryptophane (L- and DL-forms).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5920   Tyrosine.
 top

(a) Product. Tyrosine (L- and DL-forms).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5925   Valine.
 top

(a) Product. Valine (L- and DL-forms).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5930   Vitamin A.
 top

(a) Product. Vitamin A.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5933   Vitamin A acetate.
 top

(a) Product. Vitamin A acetate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5936   Vitamin A palmitate.
 top

(a) Product. Vitamin A palmitate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5945   Vitamin B12.
 top

(a) Product. Vitamin B12.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5950   Vitamin D2.
 top

(a) Product. Vitamin D2.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5953   Vitamin D3.
 top

(a) Product. Vitamin D3.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5985   Zinc chloride.
 top

(a) Product. Zinc chloride.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5988   Zinc gluconate.
 top

(a) Product. Zinc gluconate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5991   Zinc oxide.
 top

(a) Product. Zinc oxide.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5994   Zinc stearate.
 top

(a) Product. Zinc stearate prepared from stearic acid free from chick-edema factor.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5997   Zinc sulfate.
 top

(a) Product. Zinc sulfate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

Subpart G—Sequestrants2
top
§ 582.6033   Citric acid.
 top

(a) Product. Citric acid.

2 For the purpose of this subpart, no attempt has been made to designate those sequestrants that may also function as chemical preservatives.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6085   Sodium acid phosphate.
 top

(a) Product. Sodium acid phosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6099   Tartaric acid.
 top

(a) Product. Tartaric acid.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6185   Calcium acetate.
 top

(a) Product. Calcium acetate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6193   Calcium chloride.
 top

(a) Product. Calcium chloride.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6195   Calcium citrate.
 top

(a) Product. Calcium citrate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6197   Calcium diacetate.
 top

(a) Product. Calcium diacetate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6199   Calcium gluconate.
 top

(a) Product. Calcium gluconate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6203   Calcium hexametaphosphate.
 top

(a) Product. Calcium hexametaphosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6215   Monobasic calcium phosphate.
 top

(a) Product. Monobasic calcium phosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6219   Calcium phytate.
 top

(a) Product. Calcium phytate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6285   Dipotassium phosphate.
 top

(a) Product. Dipotassium phosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6290   Disodium phosphate.
 top

(a) Product. Disodium phosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6386   Isopropyl citrate.
 top

(a) Product. Isopropyl citrate.

(b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 0.02 percent in accordance with good manufacturing or feeding practice.

§ 582.6511   Monoisopropyl citrate.
 top

(a) Product. Monoisopropyl citrate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6625   Potassium citrate.
 top

(a) Product. Potassium citrate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

[41 FR 38657, Sept. 10, 1976. Redesignated at 42 FR 14091, Mar. 15, 1977]

§ 582.6751   Sodium citrate.
 top

(a) Product. Sodium citrate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

[41 FR 38657, Sept. 10, 1976. Redesignated at 42 FR 14091, Mar. 15, 1977]

§ 582.6754   Sodium diacetate.
 top

(a) Product. Sodium diacetate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6757   Sodium gluconate.
 top

(a) Product. Sodium gluconate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6760   Sodium hexametaphosphate.
 top

(a) Product. Sodium hexametaphosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6769   Sodium metaphosphate.
 top

(a) Product. Sodium metaphosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6778   Sodium phosphate.
 top

(a) Product. Sodium phosphate (mono-, di-, and tribasic).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6787   Sodium pyrophosphate.
 top

(a) Product. Sodium pyrophosphate.

(b) Condition of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6789   Tetra sodium pyrophosphate.
 top

(a) Product. Tetra sodium pyrophosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6801   Sodium tartrate.
 top

(a) Product. Sodium tartrate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6804   Sodium potassium tartrate.
 top

(a) Product. Sodium potassium tartrate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6807   Sodium thiosulfate.
 top

(a) Product. Sodium thiosulfate.

(b) Tolerance. 0.1 percent.

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in salt in accordance with good manufacturing or feeding practice.

§ 582.6810   Sodium tripolyphosphate.
 top

(a) Product. Sodium tripolyphosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6851   Stearyl citrate.
 top

(a) Product. Stearyl citrate.

(b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 0.15 percent in accordance with good manufacturing or feeding practice.

Subpart H—Stabilizers
 top
§ 582.7115   Agar-agar.
 top

(a) Product. Agar-agar.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.7133   Ammonium alginate.
 top

(a) Product. Ammonium alginate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.7187   Calcium alginate.
 top

(a) Product. Calcium alginate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.7255   Chondrus extract.
 top

(a) Product. Chondrus extract (carrageenin).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.7330   Gum arabic.
 top

(a) Product. Acacia (gum arabic).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.7333   Gum ghatti.
 top

(a) Product. Gum ghatti.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.7339   Guar gum.
 top

(a) Product. Guar gum.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.7343   Locust bean gum.
 top

(a) Product. Locust (carob) bean gum.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.7349   Sterculia gum.
 top

(a) Product. Sterculia gum (karaya gum).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.7351   Gum tragacanth.
 top

(a) Product. Tragacanth (gum tragacanth).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.7610   Potassium alginate.
 top

(a) Product. Potassium alginate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.7724   Sodium alginate.
 top

(a) Product. Sodium alginate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

Browse Previous |  Browse Next






















chanrobles.com