21 C.F.R. § 520.2455 Tiamulin.
Title 21 - Food and Drugs
(a) Specifications. (1) Each ounce of concentrate solution contains 3.64 grams (12.3 percent) tiamulin hydrogen fumarate. (2) Each gram of soluble powder contains 450 milligrams (mg) tiamulin hydrogen fumarate. (b) Sponsors. See Nos. 058198 and 059130 in §510.600(c) of this chapter. (c) Related tolerances. See §556.738 of this chapter. (d) Special considerations. (1) Swine being treated with tiamulin should not have access to feeds containing polyether ionophores (e.g., lasalocid, monensin, narasin, salinomycin, or semduramycin) as adverse reactions may occur. (2) Do not use in swine weighing over 250 pounds (lb). (e) Conditions of use in swine—(1) Amounts and indications for use. Administer in drinking water for 5 consecutive days: (i) 3.5 mg per (/) lb of body weight daily for treatment of swine dysentery associated with Brachyspira hyodysenteriae susceptible to tiamulin. (ii) 10.5 mg/lb of body weight daily for treatment of swine pneumonia due to Actinobacillus pleuropneumoniae susceptible to tiamulin. (2) Limitations. Withdraw medication 3 days before slaughter following treatment at 3.5 mg/lb and 7 days before slaughter following treatment at 10.5 mg/lb of body weight. Prepare fresh medicated water daily. Use as only source of drinking water. [70 FR 75017, Dec. 19, 2005]
Title 21: Food and Drugs
PART 520—ORAL DOSAGE FORM NEW ANIMAL DRUGS
§ 520.2455 Tiamulin.
