42 C.F.R. § 81.23   Guidelines for cancers for which primary site is unknown.


Title 42 - Public Health


Title 42: Public Health
PART 81—GUIDELINES FOR DETERMINING PROBABILITY OF CAUSATION UNDER THE ENERGY EMPLOYEES OCCUPATIONAL ILLNESS COMPENSATION PROGRAM ACT OF 2000
Subpart E—Guidelines To Estimate Probability of Causation

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§ 81.23   Guidelines for cancers for which primary site is unknown.

(a) In claims for which the primary cancer site cannot be determined, but a site of metastasis is known, DOL will calculate probability of causation estimates for various likely primary sites. Table 1, below, indicates the primary cancer site(s) DOL will use in NIOSH-IREP when the primary cancer site is unknown.

Table 1

Primary cancers (ICD–9 codes3 ) for which probability of causation is to be calculated, if only a secondary cancer site is known. “M” indicates cancer site should be used for males only, and “F” indicates the cancer site should be used for females only. A glossary of cancer descriptions for each ICD–9 code is provided in Appendix A to this part.

3 The International Classification of Diseases Clinical Modification (9th Revision) Volume I&II. [1991] Department of Health and Human Services Publication No. (PHS) 91–1260, U.S. Government Printing Office, Washington D.C.

------------------------------------------------------------------------Secondary cancer (ICD-9 code)     ICD-9 code of likely primary cancers------------------------------------------------------------------------Lymph nodes of head, face and  141, 142 (M), 146 (M), 149 (F), 161 (M), neck (196.0).                  162, 172, 173, 174 (F), 193 (F).Intrathoracic lymph nodes      150 (M), 162, 174 (F). (196.1).Intra-abdominal lymph nodes    150 (M), 151 (M), 153, 157 (F), 162, 174 (196.2).                       (F), 180 (F), 185 (M), 189, 202 (F).Lymph nodes of axilla and      162, 172, 174 (F). upper limb (196.3).Inguinal and lower limb lymph  154 (M), 162, 172, 173 (F), 187 (M). nodes (196.5).Intrapelvic lymph nodes        153 (M), 154 (F), 162 (M), 180 (F), 182 (196.6).                       (F), 185 (M), 188.Lymph nodes of multiple sites  150 (M), 151 (M), 153 (M), 162, 174 (F). (196.8).Lymph nodes, site unspecified  150 (M), 151, 153, 162, 172, 174 (F), 185 (196.9).                       (M).Lung (197.0).................  153, 162, 172 (M), 174 (F), 185 (M), 188                                (M), 189.Mediastinum (197.1)..........  150 (M), 162, 174 (F).Pleura (197.2)...............  150 (M), 153 (M), 162, 174 (F), 183 (F),                                185 (M), 189 (M).Other respiratory organs       150, 153 (M), 161, 162, 173 (M), 174 (F), (197.3).                       185 (M), 193 (F).Small intestine, including     152, 153, 157, 162, 171, 172 (M), 174 duodenum (197.4).              (F), 183 (F), 189 (M).Large intestine and rectum     153, 154, 162, 174 (F), 183 (F), 185 (M). (197.5).Retroperitoneum and            151, 153, 154 (M), 157, 162 (M), 171, 174 peritoneum (197.6).            (F), 182 (F), 183 (F).Liver, specified as secondary  151 (M), 153, 154 (M), 157, 162, 174 (F). (197.7).Other digestive organs         150 (M), 151, 153, 157, 162, 174 (F), 185 (197.8).                       (M).Kidney (198.0)...............  153, 162, 174 (F), 180 (F), 185 (M), 188,                                189, 202 (F).Other urinary organs (198.1).  153, 174 (F), 180 (F), 183 (F), 185 (M),                                188, 189 (F).Skin (198.2).................  153, 162, 171 (M), 172, 173 (M), 174 (F),                                189 (M).Brain and spinal cord (198.3)  162, 172 (M), 174 (F).Other parts of nervous system  162, 172 (M), 174 (F), 185 (M), 202. (198.4).Bone and bone marrow (198.5).  162, 174 (F), 185 (M).Ovary (198.6)................  153 (F), 174 (F), 183 (F).Suprarenal gland (198.7).....  153 (F), 162, 174 (F).Other specified sites (198.8)  153, 162, 172 (M), 174 (F), 183 (F), 185                                (M), 188 (M).------------------------------------------------------------------------

(b) DOL will select the site producing the highest estimate for probability of causation to adjudicate the claim.

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