46 C.F.R. § 150.130 Loading a cargo on vessels carrying cargoes with which it is incompatible.
Title 46 - Shipping
Except as described in §150.160, the person in charge of a vessel shall ensure that the containment system for a cargo that is a hazardous material meets the following requirements: (a) The containment system must separate the hazardous material or its residue from any cargo in table I with which it is incompatible by two barriers such as formed by a: (1) Cofferdam; (2) Empty tank; (3) Void space; (4) Cargo handling space; (5) Tank containing a compatible cargo; or (6) Piping tunnel. (b) In this subpart, isolation across a cruciform joint is equivalent to isolation by two barriers. (c) The containment system for the hazardous material must not have a piping or venting system that connects to a containment system carrying a cargo with which the hazardous material is incompatible. Any such piping or venting system must have been separated from the containment system carrying the incompatible cargo by: (1) Removing a valve or spool piece and blanking off the exposed pipe ends, or (2) Installing two spectacle flanges in series with a means of detecting leakage into the pipe between the spectacle flanges.
Title 46: Shipping
PART 150—COMPATIBILITY OF CARGOES
§ 150.130 Loading a cargo on vessels carrying cargoes with which it is incompatible.

