21 C.F.R. Subpart D—Chemical Preservatives
Title 21 - Food and Drugs
(a) Product. Ascorbic acid. (b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice. (a) Product. Benzoic acid. (b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 0.1 percent in accordance with good manufacturing or feeding practice. (a) Product. Erythorbic acid. (b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice. (a) Product. Propionic acid. (b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice. (a) Product. Sorbic acid. (b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice. (a) Product. Thiodipropionic acid. (b) Tolerance. This substance is generally recognized as safe for use in food when the total content of antioxidants is not over 0.02 percent of fat or oil content including essential (volatile) oil content of the food, provided the substance is used in accordance with good manufacturing or feeding practice. (a) Product. Ascorbyl palmitate. (b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice. (a) Product. Butylated hydroxyanisole. (b) Tolerance. This substance is generally recognized as safe for use in food when the total content of antioxidants is not over 0.02 percent of fat or oil content, including essential (volatile) oil content of food provided the substance is used in accordance with good manufacturing or feeding practice. (a) Product. Butylated hydroxytol- uene. (b) Tolerance. This substance is generally recognized as safe for use in food when the total content of antioxidants is not over 0.02 percent of fat or oil content, including essential (volatile) oil content of food provided the substance is used in accordance with good manufacturing or feeding practice. (a) Product. Calcium ascorbate. (b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice. (a) Product. Calcium propionate. (b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice. (a) Product. Calcium sorbate. (b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice. (a) Product. Dilauryl thiodipropionate. (b) Tolerance. This substance is generally recognized as safe for use in food when the total content of antioxidants is not over 0.02 percent of fat or oil content, including essential (volatile) oil content of the food, provided the substance is used in accordance with good manufacturing or feeding practice. (a) Product. Gum guaiac. (b) Tolerance. 0.1 percent (equivalent antioxidant activity 0.01 percent). (c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in edible fats or oils in accordance with good manufacturing or feeding practice. (a) Product. Methylparaben (methyl p-hydroxybenzoate). (b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 0.1 percent in accordance with good manufacturing or feeding practice. (a) Product. Potassium bisulfite. (b) [Reserved] (c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice, except that it is not used in meats or in food recognized as source of vitamin B1. (a) Product. Potassium metabisulfite. (b) [Reserved] (c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice, except that it is not used in meats or in food recognized as source of vitamin B1. (a) Product. Potassium sorbate. (b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice. (a) Product. Propyl gallate. (b) Tolerance. This substance is generally recognized as safe for use in food when the total content of antioxidants is not over 0.02 percent of fat or oil content, including essential (volatile) oil content of the food, provided the substance is used in accordance with good manufacturing or feeding practice. (a) Product. Propylparaben (propyl p-hydroxybenzoate). (b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 0.1 percent in accordance with good manufacturing or feeding practice. (a) Product. Sodium ascorbate. (b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice. (a) Product. Sodium benzoate. (b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 0.1 percent in accordance with good manufacturing or feeding practice. (a) Product. Sodium bisulfite. (b) [Reserved] (c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice, except that it is not used in meats or in food recognized as source of vitamin B1. (a) Product. Sodium metabisulfite. (b) [Reserved] (c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice, except that it is not used in meats or in food recognized as source of vitamin B1. (a) Product. Sodium propionate. (b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice. (a) Product. Sodium sorbate. (b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice. (a) Product. Sodium sulfite. (b) [Reserved] (c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice, except that it is not used in meats or in food recognized as source of vitamin B1. (a) Product. Stannous chloride. (b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 0.0015 percent calculated as tin in accordance with good manufacturing or feeding practice. (a) Product. Sulfur dioxide. (b) [Reserved] (c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice, except that it is not used in meats or in food recognized as source of vitamin B1. (a) Product. Tocopherols. (b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
Title 21: Food and Drugs
PART 582—SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart D—Chemical Preservatives
§ 582.3013 Ascorbic acid.
§ 582.3021 Benzoic acid.
§ 582.3041 Erythorbic acid.
§ 582.3081 Propionic acid.
§ 582.3089 Sorbic acid.
§ 582.3109 Thiodipropionic acid.
§ 582.3149 Ascorbyl palmitate.
§ 582.3169 Butylated hydroxyanisole.
§ 582.3173 Butylated hydroxytoluene.
§ 582.3189 Calcium ascorbate.
§ 582.3221 Calcium propionate.
§ 582.3225 Calcium sorbate.
§ 582.3280 Dilauryl thiodipropionate.
§ 582.3336 Gum guaiac.
§ 582.3490 Methylparaben.
§ 582.3616 Potassium bisulfite.
§ 582.3637 Potassium metabisulfite.
§ 582.3640 Potassium sorbate.
§ 582.3660 Propyl gallate.
§ 582.3670 Propylparaben.
§ 582.3731 Sodium ascorbate.
§ 582.3733 Sodium benzoate.
§ 582.3739 Sodium bisulfite.
§ 582.3766 Sodium metabisulfite.
§ 582.3784 Sodium propionate.
§ 582.3795 Sodium sorbate.
§ 582.3798 Sodium sulfite.
§ 582.3845 Stannous chloride.
§ 582.3862 Sulfur dioxide.
§ 582.3890 Tocopherols.
